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Lipolysis

OBJECTIVE: TO CONTROL THE AMOUNT OF STORED FAT

Fat control is ensured by three mechanisms:

  • Adipogenesis – synthesis of adipose tissue
  • Lipogenesis – absorption and storage of fats
  • Lipolysis – fat excretion
fat control controle graisse

These three mechanisms occur in adipocytes but have very different regulatory mechanisms.

Lipolysis allows the degradation of triglycerides

In adipocytes, fat is stored as triglycerides within lipid droplets. It is degraded into fatty acid and glycerol by the action of an enzyme: triglyceride lipase.

Triglyceride lipase is activated by cyclic adenosine monophosphate (cAMP). The latter is synthesized from ATP by adenyl cyclase and is degraded to 5’AMP by the phosphodiesterase.

lipolysis-lipolyse

CONSUMERS’ EXPECTATIONS

  • Controling the amount of stored fat
  • Increasing the amount of excreted fat

EXSYMOL’S ANSWER

To meet these expectations, Exsymol has developed active agents that stimulate lipolysis. This increases the fat excretion for a firmer and a slimmer silhouette.

Increasing lipolysis for maximizing fat elimination

Stimulating adenylcyclase for increasing cAMP synthesis

By stimulating the activity of adenylcyclase, the amount of cAMP synthesized and therefore the amount of triglyceride lipase responsible for cleaving triglycerides into fatty acids and glycerol is increased.

Algisium

Liposiliol

Cafeisilane

Theophilisilane

Inhibiting phosphodiesterase for maintaining the amount of cAMP

By inhibiting phosphodiesterase, degradation of cAMP into 5’AMP is avoided. This ensures a good activation of the triglyceride lipase. Xanthic bases are known to inhibit phosphodiesterase.

Cafeisilane

Theophilisilane

Stimulating lipolysis for a slimming effect

By stimulating lipolysis, it reduces fat for a refined silhouette.

Algisium

Arct’Alg

Cafeisilane

Slimagine

Improving cell communication helps increasing lipolysis

Nerve cells from the hypodermis stimulate the lipolytic activity of adipocytes

Nerve cells play a key role in cell communication. In the hypodermis, they promote the lipolytic activity of adipocytes.

Ensuring the survival of the nerve cells in the hypodermis ensures good lipolysis for a slimming action.

Glutrapeptide

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