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MeiYanoL

Combats under-eye shadows

Prevents an accumulation of red blood cells – iron binder

Combats under-eye bags

Prevents an accumulation of plasma – anti-inflammatory

Your needs

The eye area is a priority target for cosmetics and rightly so, as it is one of the most sensitive areas of the face. The skin around the eyes is very thin, and provides less protection against environmental stress (UV, pollution, tiredness, etc.) and this is manifested particularly in the appearance of two symptoms: shadows and bags. These unsightly imperfections accentuate signs of tiredness and make the face look older.

  • Shadows are mainly due to an accumulation of red blood cells in the peri-orbital area
  • Bags are mainly due to an accumulation of plasma in the peri-orbital area

The aim is to limit the appearance of inflammation which leads to chronic under-eye bags and shadows and finally skin breakdown: dryness, lines, etc.

EXSYMOL’s answer

How it works

Under-eye shadows and bags are mainly caused by an inflammatory reaction in three stages:

  • Stress (UV, pollution, aging, etc.) and an accumulation of iron (already existing under-eye bags and shadows) generate ROSs which trigger an inflammatory reaction.
  • The metabolism reacts to the inflammatory reaction by recruiting white blood cells circulating in the blood vessels to act at the site of inflammation.
  • The moving of white blood cells from micro-circulation to the inflammatory site on the skin requires pores to be formed on blood vessel wells. This mechanism causes a leak of plasma and of a multitude of red blood cells in the surrounding tissue.

The accumulation of plasma leads to the appearance of under-eye bags (edema), while the hemoglobin contained in the red blood cells colors the tissue. The oxidation of iron in hemoglobin increases the color characteristic of under-eye shadows.

MeiYanoL can prevent inflammation and porosity of blood vessels, reducing under-eye shadows and bags.

General properties

MeiYanoL (INCI name: SAMBUCUS NIGRA FLOWER EXTRACT) is an eco-friendly extract of elderflower developed in collaboration with perfumers in the Grasse area (France).

MeiYanoL is obtained using biorefining techniques and optimized extraction processes to maximize flavonoid and polyphenol content.

Cosmetic benefits

Consumer benefits

  • Combats under-eye shadows
  • Combats under-eye bags/edema
  • Anti-redness

Skin benefits

  • Anti-oxidant
  • Traps iron
  • Prevents inflammation
  • Prevents micro-circulation porosity

Our added value

  • Eco-friendly active ingredient produced in partnership with a perfumer in Grasse (France) – zero waste
  • Acts directly on the mechanism responsible for under-eye shadows and bags

The expert’s opinion

Under-eye shadows and bags are mainly caused by an inflammatory reaction in three stages:

Under-eye shadows and bags are mainly caused by an inflammatory reaction in three stages:

  1. Stress (UV, pollution, aging, etc.) triggers an inflammatory reaction.
  2. Inflammation is also responsible for the expression of anchoring proteins which bind white blood cells at the inflammatory site.
  3. This binding leads to pores appearing in the blood vessel wall so that the white blood cells can migrate into the dermis. This mechanism also causes a leak of plasma and of a multitude of red blood cells in the surrounding tissue.

The accumulation of plasma provokes the appearance of under-eye bags (edema) and the leakage of red blood cells generates red coloring and under-eye shadows.

MeiYanoL can reduce the expression of anchoring proteins which limits the forming of pores and the leakage of red blood cells and plasma, reducing under-eye shadows and bags.

Under-eye bags and shadows are symptoms originating from many factors

There are many reasons for shadows: inflammation, fat accumulation, overproduction of melanin.

The chronic nature of under-eye shadows and bags will accentuate signs of tiredness and make furrows over the years.

We offer complementary solutions for an overall eye area approach, proven by a clinical trial carried out by combining MeiYanoL with our SILANOLS technology

The forming of under-eye bags and shadows involves several mechanisms:

-> MeiYanoL acts on several levels:

MeiYanoL is a powerful anti-oxidant which protects very vulnerable skin.

Its capacity to trap iron inhibits certain oxidation mechanisms, and contributes to limiting the color of shadows.

MeiYanoL also interferes with signaling channels involved in the hyperpermeability of micro-vessels.

The presence of rutin contributes to strengthening micro-vessel walls.

-> We offer complementary solutions for an overall eye area approach. A clinical trial proved the effectiveness of a combination of MeiYanoL and a SILANOL which restructures tissue.

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